According to Official Guinness Records,
The fastest marathon on crutches was 6 hr 24 min 48 sec by John Sandford Hart (UK) at the 2011 Virgin London Marathon in London, UK, on 17 April 2011.
Sandford Hart uses a prosthetic right leg after having it amputated in 2009. This record is for the use of two legs on crutches, while a separate category is monitored for only allowing one foot to touch the ground the entire race.
For a complete list of 2011 records, please visit 2011 Guinness Records in United Kingdom.